In October 2024, NASA’s Office of the Chief Health and Medical Officer (OCHMO) initiated a working group to review the status and progress of research and clinical activities intended to mitigate the risk of venous thromboembolism (VTE) during spaceflight. The working group took place over two days at NASA’s Johnson Space Center; a second meeting […]
Category: Human Health and Performance
Human System Risk Board
Risk is inherent in human spaceflight. However, specific risks can and should be understood, managed, and mitigated to reduce threats posed to astronauts. Risk management in the context of human spaceflight can be viewed as a trade-based system. The relevant evidence in life sciences, medicine, and engineering is tracked and evaluated to identify ways to […]
Risk to Vehicle Crew Egress Capability and Task Performance as Applied to Earth and Extraterrestrial Landings
New spacecraft that will transport crews to the Lunar and Martian surfaces and return them to Earth may have diverse landing modalities which will function in different landing environments. Additionally, the crew may be deconditioned on landing, impacting their ability to independently egress the vehicles, perform post-landing tasks in a timely manner, and perform surface […]
Risk to Crew Health Due to Electrical Shock (Electrical Shock Risk)
It is important to protect humans from unintended electrical current flow during spaceflight. The thresholds for contact electrical shock are well established, and standards and requirements exist that minimize the probability of contact electrical shock. Current thresholds were chosen (vs. voltage thresholds) because body impedance varies depending on conditions such as wet/dry, AC/DC, voltage level, […]
Risk of Urinary Retention
Exposure to the altered gravity in the spaceflight environment may cause physiological changes. One of these changes is the inability to completely empty the bladder or urinary retention. Causes of urinary retention in the early phases of flight include altered baseline physiology seen with exposure to microgravity, the anticholinergic side effects of medications that are […]
Risk of Toxic Substance Exposure
Safe, breathable air is essential for crew health. Human spaceflight has involved toxicological events ranging in severity from trivial to life-threatening. Toxic exposure to chemical contaminants can originate from environmental system leaks, payload leaks, pyrolysis of polymeric materials, off-gassing of polymeric materials, use of utility compounds, propellant entry, microbial products, and human metabolism. To ensure […]
Risk of Spaceflight Associated Neuro-ocular Syndrome
Exposure to altered gravity can cause ocular and brain structural changes to develop during spaceflight; these changes could lead to vision alterations, cognitive effects, or other deleterious health effects. SANS is a syndrome unique to humans that fly in space, and there is no terrestrial disease equivalent. Brain structural changes appear small but seem to […]
Risk of Renal Stone Formation
Exposure to microgravity induces bone atrophy/bone loss which increases circulating calcium, impacting the renal stone risk. Risk mitigation strategies including exercise and hydration are well-defined although the ability to treat a renal stone during exploration missions is not yet available. Directed Acyclic Graph Files + DAG File Information (HSRB Home Page) + Risk of Renal Stone Formation […]
Risk of Reduced Physical Performance Capabilities Due to Reduced Muscle Size, Strength, and Endurance (Muscle Risk)
Exposure to the microgravity environment causes muscle size, strength, and endurance to decline. Based on ISS data, if crew adhere to the exercise schedule and have access to adequate exercise countermeasure systems then on average, they return with minimal losses of muscle size, strength, and endurance. New exploration countermeasures systems will be different from ISS […]
Risk of Reduced Physical Performance Capabilities Due to Reduced Aerobic Capacity (Aerobic Risk)
Spaceflight causes measures of maximum aerobic capacity to decline, which can result in impaired mission task performance. Based on ISS data, if crew adhere to existing exercise schedules and have access to adequate exercise countermeasure systems, then on average, they return with minimal losses of aerobic fitness. New exploration countermeasures systems will be different from […]